Ionis Pharmaceuticals Down 26%, On Pace For Largest Percent Decrease Since May 2016 -- Data Talk

Ionis Pharmaceuticals, Inc. (IONS) is currently at $29.17, down $10.25 or 26%

--Would be lowest close since April 23, 2025, when it closed at $29.10

--On pace for largest percent decrease since May 26, 2016, when it fell 39.42%

--Currently down seven of the past eight days

--Down 32.97% month-to-date

--Down 63.13% year-to-date; on pace for worst year since 2002, when it fell 70.3%

--Down 66.28% from its all-time closing high of $86.50 on Feb. 6, 2026

--Down 58.05% from 52 weeks ago (Nov. 10, 2025), when it closed at $69.54

--Down 66.28% from its 52-week closing high of $86.50 on Feb. 6, 2026

--Would be a new 52-week closing low

--Traded as low as $28.05; lowest intraday level since April 21, 2025, when it hit $27.90

--Down 28.84% at today's intraday low; largest intraday percent decrease since May 26, 2016, when it fell as much as 40.19%

All data as of 10:02:37 AM ET

Source: Dow Jones Market Data, FactSet

(END) Dow Jones Newswires

November 09, 2026 10:05 ET (15:05 GMT)